Quetiapine (Seroquel) was more clinically effective than lithium as a first-line augmentation option in treatment-resistant depression and likely was more cost-effective, a pragmatic multicenter ...

"Compared with lithium, quetiapine might be a more appropriate first-line augmentation for many people with treatment-resistant depression. Future research should investigate predictors of ...

A recent study published in the New England Journal of Medicine looked at the effect of combining existing antidepressants with an antipsychotic or the mood-stabilizing drug lithium, compared to ...

Doctors may prescribe lithium, an antimanic drug, or an antipsychotic drug -- or a combination of both -- in order to alleviate symptoms of depression without triggering a manic episode.

Traditional antidepressants are considered "experimental" for treating bipolar depression in that none has been proven to be more effective than a placebo (sugar pill) in bipolar I disorder.

In this phase, patients taking antidepressants such as Prozac, Lexapro and Zoloft were treated with lithium or nortriptyline -- medications that were widely used before those other, newer ...

A groundbreaking discovery has highlighted lithium - a drug long used to treat bipolar disorder and depression - as a potential therapy for autism spectrum disorder (ASD). This research ...

Augmentation was more effective with quetiapine than lithium for treatment-resistant depression in a pragmatic trial. Quetiapine also improved quality-adjusted life years more than lithium.