Background Abnormalities of type I interferon signaling and production can initiate lupus development. Disturbances of nucleic acid-sensing molecules triggered autoreactivity in lupus mouse models.

Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable presentations, course and prognosis. We sought to develop evidence-based recommendations addressing the major issues in ...

If you live with heartburn or acid reflux, you are likely taking medication to manage it. Proton pump inhibitor (PPIs) drugs are medications that reduce gastric acid secretions, and include popular ...

Objective BAFF and APRIL signal through TACI, BCMA, and/or BAFF-R, and play important roles in the activation, differentiation, and/or survival of B cells, particularly antibody-secreting cells, as ...

Since survival of patients with systemic lupus erythematosus (SLE) has improved over the past decades, increasing attention is focused on complications of the disease. Osteoporosis and fractures ...

Background: A number of families have been described which include multiple members with symptomatic, endoscopic, or complicated gastro-oesophageal reflux disease (GORD). First degree relatives of ...

More than 40% of patients with systemic lupus erythematosus in a large international study reported insufficient levels of physical activity, with low activity levels correlated to worsening of ...

Ms. Le, 36, was diagnosed with lupus in 2016, just after she got married. She tried all the standard treatments, hoping that her symptoms would stabilize and she could one day get pregnant.

“Lupus nephritis disproportionately affects younger women, mostly women of color, often leading to end-stage kidney disease,” said Levi Garraway, M.D., Ph.D., chief medical officer and head of ...

The Moniteau County Historical Society held their June 9 meeting at the Lupus Baptist Church. Over 50 members and guests were given a timeline of Lupus history by Virginia Brizendine. She grew up ...

Are people eating out less because of trade-war heartburn? Here's what we know. Provided by Dow Jones Jun 17, 2025, 8:45:00 AM ...

Healthy eating can make a big difference in your lupus symptoms and your overall health. It can also help prevent or manage other health conditions you may have, like high blood pressure or diabetes.