Using a controllable membrane engineering strategy, researchers prepared exosomes with different cholesterol contents, such as milk exosomes, ginger exosomes, and tumor cell-derived exosomes.

In summary, the successful modulation of cholesterol content in exosome membranes to promote membrane fusion-mediated cargo transfer offers exciting opportunities for the development of safer and ...

An exosome can be broadly defined as a 40–100 nm diameter membrane vesicle of endocytic origin released by most cells upon fusion of the multivesicular bodies with the plasma membrane ...

(a) Fe3+ ion triggers membrane fusion in exosomes tailored with catechol (CEx). The formation of a metal-catechol complex brings the exosomes into close proximity and enables fusion. Different ...

The HA-exosome interaction is expected to be similar to HA-endosome interaction during membrane fusion. During the interaction, conformational change of HA was found again before its docked on an ...

Researchers from the Verstreken lab have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body.

Exosomes are vesicles, or cellular components, that exist outside of a cell. They are generally understood as having been released from cells upon fusion with an intermediate endocytic compartment ...

Exosomes are a class of cell-derived extracellular vesicles of endosomal origin, and are typically 30-150 nm in diameter – the smallest type of extracellular vesicle. In this article, we explore ...