6 Finally, when they grafted these organoids into mammary fat pads cleared of their native tissue in nude mice, the organoids reconstituted to form mammary glands in the mouse. “It has been a ...

"We show that treatment of 4T1-12B mouse breast cancer cells with this ... implanted with 4T1-12B cells orthotopically in the mammary fat pad inhibited the metastasis of tumor cells to the lungs.

The researchers examined irradiated mouse mammary fat pads and developed mammary-derived hydrogels to seed tumor cell lines into the animal models. This allowed them to assess and evaluate tumor ...

Researchers explore the role of a high-fat diet in promoting the formation of premetastatic niches and platelet activation.