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By Nina Agrawal The news made for an alarming headline this week: Research showed that common chemicals in plastics were associated with 350,000 heart disease deaths across the world in 2018.

After withdrawal of treatment, relapse of Paget's disease, as judged by rising levels ... bisphosphonates do not prevent the recruitment of osteoclasts. The kinetics of relapse (as judged by ...

Specialized cells known as osteoclasts degrade the bone and ... which renews and strengthens the skeletal structure. In Paget’s disease, the balance between bone removal and bone building ...

In Paget’s disease, the balance between bone removal ... Specialized cells known as osteoclasts degrade the bone and facilitate the absorption of the resulting minerals, primarily calcium ...

Specialized cells known as osteoclasts degrade the bone and facilitate the absorption ... It fills in the gaps with new bone, which renews and strengthens the skeletal structure. In Paget's disease, ...

Background and objectives Paget disease (PD), also known as osteitis deformans, is characterised by single or multiple bone site alteration, including accelerated osteoclast-mediated resorption ...

Excessive activity of osteoclasts causes many diseases such as osteoporosis, periprosthetic osteolysis, bone tumors, and Paget’s disease. In contrast, osteopetrosis results from osteoclast deficiency.

Blocking osteoclasts from removing bone cells allows bones to ... In addition to osteoporosis treatment, Reclast has other FDA-approved indications, including treating Paget's disease and preventing ...

The cause of the disease appears to be a defect in bone reabsorption by the osteoclast, a specialized cell that normally helps maintain bone health. Paget’s disease is not a cancer. It is ...