Leaders from the world of cell and gene therapy shared their personal stories and policy recommendations in an extraordinary roundtable conducted by the FDA in front of its recently-appointed top ...

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The ...

"Sickle cell disease is a devasting disorder that affects approximately 100,000 people in the U.S., leading to anemia, severe ...

Two groundbreaking biotechnology advances are fundamentally altering human health and food production in 2025, moving from ...

Abstract: Tandem repeats in genomic sequences are characterized by two or more contiguous copies of a pattern of nucleotides. The role of these repeats as molecular markers is well established in ...

We introduce MADna, a sequence-dependent coarse-grained model of double-stranded DNA (dsDNA), where each nucleotide is described by three beads localized at the sugar, at the base moiety, and at the ...

Beam Therapeutics (NASDAQ: BEAM) , a biotechnology firm pioneering precision genetic medicines via base editing, announced it will present updated da ...

We consider construction of a set of smaller 4 × 4 matrices to represent DNA primary sequences which are based on enumeration of all 64 triplets of nucleic acids bases. The leading eigenvalue from the ...

G ene therapy has always held enormous promise to correct genetic diseases, but turning that potential into treatments has been challenging.

BEAM-101 is an investigational genetically modified ex vivo cell therapy for ... at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable ...

Sickle cell habitus, the distinct physical features of some people with sickle cell disease, are typically associated with patients who have more severe forms of the disease, such as sickle cell ...