circLOC375190 affects AIS autophagy by regulating the mTORC1/TFEB axis. Therefore, to provide a theoretical foundation for the treatment of AIS, the authors explored the specific mechanism of ...

State Key Laboratory of Swine and Poultry Breeding Industry, South China Agricultural University, Guangzhou, Guangdong 510642, China Guangdong Academy of Agricultural Sciences, Guangzhou, Guangdong ...

Scientists have created a new nanoparticle that could make ultrasound-based cancer treatments more effective and safer, while also helping prevent tumors from coming back. To make the therapy even ...

The fatty acid (FA) transporter CD36 (FA translocase/cluster of differentiation 36) is the gatekeeper of cardiac FA metabolism. Preferential localization of CD36 to the sarcolemma is one of the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The molecular mechanisms behind brown adipose ...

Prior to this study, our understanding of the lysosomal damage response was largely limited to the processes of repair and elimination of damaged lysosomes, as well as the activation and function of ...