This study reports that activation of TFEB promotes lysosomal exocytosis and clearance of cholesterol from lysosomes, the strength of evidence for which is convincing with appropriate and validated ...

Type 1 diabetes occurs when the immune system attacks pancreatic beta cells. Type 2 diabetes happens when the body cannot use insulin effectively. The two types differ in symptoms, causes ...

Body Dimensions 145 x 70.4 x 8.6 mm (5.71 x 2.77 x 0.34 in) ...

Pradeep Ranganathan's new film 'Dragon' premiered on February 21, 2025, earning Rs 6 crore on its first day. The romantic comedy-drama saw impressive occupancy rates, especially during night shows.

Season 1 of Reacher was an adaptation of Lee Child’s first Jack Reacher novel, Killing Floor, while Season 2 was based on Bad Luck and Trouble. The first 20 minutes of Reacher Season 3 play out ...

Der USV Nappersdorf schlägt noch einmal am Deadline Day zu. Osman Caliskan wird bis Saisonende vom FC Torin (1. Klasse A) ausgeliehen. Damit reagiert die sportliche Leitung des USV auf den ...

for 1 h. Following primary antibodies were used: affinity-purified rabbit anti-TFEB antibody A303-673A (RRID: AB_11204751, 1:1000, Bethyl Laboratories, Hamburg, Germany), monoclonal anti-β/slow myosin ...

Autophagy is involved in many physiological processes. Transcription factor EB (TFEB) is a master regulator of autophagy and coordinates the expression of autophagic proteins, lysosomal hydrolases, ...