A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

Cautious reporting choices can artificially enhance how well analyses of brain activity reflect conscious and unconscious experiences, making distinguishing between the two more challenging.

Hemodynamic occlusion introduces a spatially heterogenous confound to activity measurements using two-photon and widefield imaging in mouse cortex, and needs to be taken into consideration when ...

Researchers have revealed the fundamental mechanisms underlying homologous recombination – one of the main DNA repair pathways in human cells.

A new study has shown that lowering levels of a protein called EMC10 can restore brain function and memory in models of 22q11.2 Deletion Syndrome, pointing to a potential treatment approach.

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

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